“Evaluation of in vitro antioxidant and free radical scavenging activity of leaf and twig endophytic fungal extract from Mappia foetida”

Abstract

The present study was aimed to investigate the in vitro free radical scavenging activity of leaf extracts. In vitro free radical scavenging activities of the endophytic extracts were assessed against DPPH and hydroxylradicals. The metal chelating activity and reducing power ability of the extracts of M. foetida. were also determined. The free radical scavenging activity was found to be high in methanolic extract for DPPH and hydroxyl radicals. The difference in scavenging potential of the endophytic extracts may be due to variation in the percentage of phytoconstituents extracted in methanolic solvents. Thus, the result suggests that the methanolic leaf extract of M. foetida could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases.