In Silico study using Toxtree (TT) Cramer decision tree scheme for different Isomers of Resmethrin -a Type-I Synthetic Pyrethroid

Abstract

Synthetic pyrethroids are widely used in household, public places and agriculture as insecticides but have harmful effect on human and the environment. The Cramer classification scheme (decision tree) is the best-known approach to estimate the Threshold of Toxicological Concern for a chemical substance based on its chemical structure. In present article we have used In silico tool Toxtree to get the Cramer class for isomers of Resmethrin. The stereochemical relationships and toxicologic and environmental effects are also discussed.