Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products

Abstract

The tiny size makes it simple to apply and remove a heating source, allowing for highly accurate temperature control along the microreactor and preventing uncontrolled dangerous exothermic reactions. This not only promotes transfer but also allows for exact monitoring of the heat exchange. Compared to a batch process, a continuous flow system makes it easier to set up and monitor reaction parameters like temperature, pressure, and flow rate, leading to a more consistent and repeatable process.7 The minimal volume needed for flow processes allows for quick screening of reaction conditions; once optimised, the reaction may be ramped up.